The Analytical report «Supporting Employment of People with Disabilities: Economic Analysis of Interventions» presents the research by an international team of experts, which they concluded within a framework of ENCON project – Enhancing CSOs Contribution to Evidence-Based Policy Making for Vulnerable Groups in Belarus. The project has been implemented by CASE Belarus in cooperation with CASE (Poland), Institute of Economic Research of Slovak Academy of Sciences (Slovakia), The Faculty of Economics and Administration of Masaryk University (Czech Republic), as well as ACT (Belarus). In the first part of paper, we describe general methodological overview based on available sources. In the second part of the paper, we describe the challenges of application of CBA on interventions for people with disabilities and present selected cases of assessment of public programmes aimed to influence their employment. Third part of the report presents cost-and-benefit analysis of an employment support program for the people with disabilities that has been recently implemented by a Belarusian NGO in Minsk.